Ready, set, wait

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Ready, set, wait

Ready, set, wait tem cell differentiation is all about cautious preparation, say Deborah Lang, Jonathan Epstein (University of Pennsylvania, Philadelphia, PA), and colleagues. They find that a transcription factor called Pax3 sends conflicting messages: it gets stem cells ready for the differentiated state, by building up proteins used in the differentiation program, but inhibits the action of ...

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Ready, Set, Verify!

Good tools can bring mechanical verification to programs written in mainstream functional languages. We use hs-to-coq to translate significant portions of Haskell’s containers library into Coq, and verify it against specifications that we derive from a variety of sources including type class laws, the library’s test suite, and interfaces from Coq’s standard library. Our work shows that it is fe...

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Ready…set…fuse

In This Issue In This Issue Ready…set…fuse he fusion of two lipid membranes underlies a huge range of biological phenomena, from infection by enveloped viruses to the secretion of cellular proteins , but a central aspect of membrane fusion has remained mysterious: do the T proteins that mediate fusion act cooperatively or independently? On page 833, Markovic et al. argue that teamwork is the or...

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Ready, set, differentiate!

The expression of E-Cadherin, a protein best known for its role in cell adhesion, regulates the onset of embryonic differentiation.

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Preview Event and team physicians reap many rewards working with highly skilled and motivated athletes. The rewards are greatest when problems are anticipated and prevented. As discussed by Drs Leonard and Townsend, the key to success for both physicians and athletes is careful and specific planning. One might say that the Boy Scout motto, "Be prepared," cannot be overemphasized in this setting.

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2005

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb1687rr4